We act with pride as members of TWOCELLS.

1.Management Philosophy

We aim to become "a global company of the 21st century that contributes to world’s healthcare and people's health through regenerative medicine."
In other words, there are four pursuits.

  1. (1) Pursue humanity (Fighting against diseases)
  2. (2) Pursue sociality (Prevail in the society)
  3. (3) Pursue economic efficiency (Contribute to the healthcare economy)
  4. (4) Pursue internationality (Act globally)

2. Message

We are a venture business company dedicated to regenerative medicine technologies to utilizing Mesenchymal Stem Cells (MSCs), which are taken from an adult body.
Since we have started our business, when regenerative medicine is not well-known, we have been engaging in developments of regenerative medicine products with MSCs for more than 20 years.

Our team have common passion (“Kokorozashi” in Japanese), which lies in “provide regenerative medicine as novel treatment options for patients with unmet medical needs.

Our Phase 3 clinical trials of gMSC1 ended in suggesting efficacy by structural evaluations with MRI and arthroscopy, although its primary endpoint failed in significance.

We of course assume that it not so easy to get an approval, for the possibility to be needed to obtain additional clinical data to discuss with regulatory authorities.

Even though, we keep on trying development of gMSC®1 to fulfill the unmet medical needs (UMNs) with our “Kokorozashi,” aiming to realize our management philosophy to become "a global company of the 21st century that contributes to world’s healthcare and people's health through regenerative medicine."

To realize our “Kokorozashi” with business growth and corporate independence, we tackle our missions.

3. Business Policy

TWOCELLS aims to be a value-creation company with "Integrated R・D・M Systems" that unitarily include Research, Development, and Marketing of MSCs-derived regenerative medicine products.

4. Meanings of the Corporate Logo

 

The TWOCELLS’ logo symbolizing “two cells” and “infinity” represents two founders who established TWOCELLS, and the limitless possibilities of medical technologies and the great hope that they bring.

Company Profile

Company Name TWOCELLS COMPANY, LIMITED
Date of Establishment April 23, 2003
Office/Laboratory 2nd Floor, Otani Building, 1-6-10 Deshio,
Minami-ku, Hiroshima 734-0001, Japan
Paid-in Capital \ 100 million (as of March 31, 2024)
Directors and Corporate Auditors Masaya Matsumoto, Representative Director
Shinichi Hasegawa, Director
Minoru Tsukamoto, Director
Yosuke Yamane, Accounting Advisor
Business activities R&D, manufacturing, and marketing(sales) of regenerative medical products and other related products (e.g. diagnostics, reagents, medical devices, etc.)

History

  1. April 2003
    Established TWOCELLS COMPANY, LIMITED in Minami-ku, Hiroshima, as a startup company from Hiroshima University

  2. August 2006
    Registered trademark of "gMSC®" (registration number 4987485)

  3. May 2008
    Started sales of serum-free medium STK®2

  4. October 2009
    Patent granted for serum-free medium for research (Patent No. 4385076),
    supported by grants from JST (Japan Science and Technology agency)

  5. February 2010
    Started sales of serum-free medium STK®1

  6. September 2010
    Started sales of serum-free medium STK®3

  7. January 2014
    Established gMSC Center, a facility for developing formulation technology, supported by grants from NEDO (New Energy and industrial technology Development Organization)

  8. March 2015
    Developed clinical-grade serum-free medium STK®1 and STK®2

  9. August 2015
    Osaka Univ. opened the MSCs Cell Bank as an achievement of Joint research with TWOCELLS

  10. April 2016
    License agreement signed with Chugai Pharmaceutical for the knee cartilage regenerative cell product “gMSC®1”

  11. May 2017
    Submitted phase III clinical trial of knee cartilage regenerative medicical product gMSC®1 (IND)

  12. October 2021
    Completed case registration of phase III clinical trial of gMSC®1

  13. April 2023
    Announced the termination of license agreements about gMSC®1 with Chugai Pharmaceuticals

  14. November 2023
    Relocation of the head office

Access

Office/Laboratory

2nd Floor, Otani Building, 1-6-10 Deshio,
Minami-ku, Hiroshima 734-0001, Japan
TEL: +81-82-256-2451 

FAX: +81-82-258-1012